Vivafree™ centrifugal filters offer fast, accurate separations of free drugs for Therapeutic Drug Monitoring. They have been used successfully for phenytoin1, valproic acid, antibiotics, immunosuppressants and other drugs. Vivafree™ filters are also being used clinically to separate free hormones such as testosterone and insulin. Separations can be performed as quickly as 20 minutes with high recoveries and excellent reproducibility. Savings of 35% have been reported when switching to Vivafree™ filters from another centrifugal ultrafiltration device2. These devices are intended for in vitro diagnostic (IVD) applications. Vivaproducts also provides centrifuges for use with these filters.
Up to 2 ml starting sample volumeFor separation of free drugs and hormones from those bound to serum proteins.
Up to 500 µl starting sample volumeFor separation of free drugs and hormones from those bound to serum proteins.
Download this Applications Note to see how Vivafree™ filters can be used to prepare samples for therapeutic drug monitoring of phenytoin, valproic acid and digoxin. They can also separate free testosterone, insulin and cortisol in clinical samples.