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Vivaspin® 4 Centrifugal Concentrator

Up to 4 ml starting volume
Concentrate up to 200x

Vivaspin 4 centrifugal devices allow rapid concentration of clinical samples up to 4 ml in volume and are intended for in vitro diagnostic (IVD) applications. The patented vertical membrane design minimizes filter fouling and the built in dead stop pocket provides maximum concentrate recovery. Vivaspin 4 devices have been used extensively to concentrate urine samples prior to gel and immunofixation electrophoresis for diagnosis of multiple myeloma, light chain amyloidosis and related blood disorders.

Data Sheet

Technical Data and Operating Instructions

Urine Protein Concentration Calculator App

CAP Validation Procedures (rev. 2/3/23)

Urine Protein Concentration with Vivaproducts Concentrators

Concentration of urine prior to electrophoresis for diagnosis of multiple myeloma and amyloidosis.
Concentrate spinal fluid prior to electrophoresis for diagnosis of meningitis and multiple sclerosis.
Protein removal from serum & cell / tissue lysates.
Exchange buffers for proteomic peptide samples.
Prepare samples for mass spectrometry.

	Time to concentrate up to 30x [min.] at 20°C	Concentrate Recovery %
Rotor	fixed angle
Centrifugal force	5,000 x g
Start volume	4 ml
BSA 1.0 mg / ml (66,000 MW)
5,000 MWCO PES	15	96%
10,000 MWCO PES	10	96%
30,000 MWCO PES	10	95%
IgG 0.25 mg / ml (160,000 MW)
30,000 MWCO PES	10	95%
50,000 MWCO PES	10	95%
100,000 MWCO PES	10	95%

Concentrator Capacity
Swing Bucket Rotor	4 ml
Fixed Angle Rotor	4 ml
Dimensions
Total Length	122 mm
Width	17 mm
Active Membrane Area	2.0 cm²
Hold-up volume, membrane and support	<10 µl
Dead stop volume	20 µl
Materials of Construction
Body	Polycarbonate
Filtrate Vessel	Polypropylene
Concentrator Cap	Polycarbonate
Membrane	Polyethersulfone

Centrifuge
Rotor Type	Swing bucket	Fixed angle
Minimum rotor angle	-	25°
Rotor Cavity	To fit 15 ml (17 mm) conical bottom tubes	To fit 15 ml (17 mm) conical bottom tubes
Maximum Speed	4,000 g	8,000 g
Concentrate Recovery
Pipette type	Fixed or variable volume	Fixed or variable volume
Recommended tip	Thin gel loader type	Thin gel loader type

Description	Prod. #	Price	Buy
10,000 MWCO, PES Membrane, 100 per pack SKU: VS0404 Price: $555.00	VS0404	$555.00	Add to Cart
10,000 MWCO, PES Membrane, 500 per pack SKU: VS0405 Price: $2,540.00	VS0405	$2,540.00	Add to Cart